In a grain-oriented electrical steel sheet manufacturing process of processing a steel slab having a predetermined composition to a final sheet thickness and then performing primary recrystallization annealing and nitriding treatment, the nitriding treatment is performed in at least two stages of temperatures including high-temperature nitriding and low-temperature nitriding, and a residence time in the high-temperature nitriding is 3 seconds or more and 600 seconds or less. In this way, nitrogen is efficiently diffused into the steel of the steel sheet before secondary recrystallization to precipitate AlN. Such a method can manufacture a grain-oriented electrical steel sheet having excellent magnetic property.