The device for packaging and dispensing a product comprises a container (12), a moveable piston (16) mounted inside the container and delimiting at least one compartment (22) containing the product, and a dispensing member (14) mounted on the container and comprising at least one outlet orifice in communication with the compartment. The container comprises an adapter portion for the dispensing member provided with an outer skirt (12d) extending from an end wall (12c) of the container, with an inner skirt (12e) radially surrounded at least in part by the outer skirt and with a wall (12f) connecting the outer and inner skirts, the wall and the skirts delimiting a groove (30) oriented axially on the side opposite to the compartment (22) and inside which the dispensing member (14) is fitted.