- 专利标题: Composition and method for imaging stem cells
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申请号: US15631124申请日: 2017-06-23
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公开(公告)号: US10920287B2公开(公告)日: 2021-02-16
- 发明人: Srabani Bhaumik , Sanjiv Sam Gambhir , Ramasamy Paulmurugan , Shahriar Yaghoubi , Byeong-Cheol Ahn , Natesh Parashurama
- 申请人: Global Life Science Solutions Operations UK Ltd , The Board of Trustees of the Leland Stanford Junior University
- 申请人地址: GB Sheffield; US CA Palo Alto
- 专利权人: Global Life Science Solutions Operations UK Ltd,The Board of Trustees of the Leland Stanford Junior University
- 当前专利权人: Global Life Science Solutions Operations UK Ltd,The Board of Trustees of the Leland Stanford Junior University
- 当前专利权人地址: GB Sheffield; US CA Palo Alto
- 代理机构: Eversheds Sutherland (US) LLP
- 主分类号: C12N15/85
- IPC分类号: C12N15/85 ; C12Q1/6897 ; C12N15/10
摘要:
An expression vector, comprising a first reporter nucleic acid sequence operably linked to a first expression control sequence comprising a promoter; and a second reporter nucleic acid sequence operably linked to a second expression control sequence that comprises a response element that is activated or inactivated as one or more of the cells differentiate or dedifferentiate. Methods and kits for imaging and monitoring stem cells comprising the expression vector are also provided.
公开/授权文献
- US20170298455A1 COMPOSITION AND METHOD FOR IMAGING STEM CELLS 公开/授权日:2017-10-19