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公开(公告)号:US10920287B2
公开(公告)日:2021-02-16
申请号:US15631124
申请日:2017-06-23
申请人: Global Life Science Solutions Operations UK Ltd , The Board of Trustees of the Leland Stanford Junior University
发明人: Srabani Bhaumik , Sanjiv Sam Gambhir , Ramasamy Paulmurugan , Shahriar Yaghoubi , Byeong-Cheol Ahn , Natesh Parashurama
IPC分类号: C12N15/85 , C12Q1/6897 , C12N15/10
摘要: An expression vector, comprising a first reporter nucleic acid sequence operably linked to a first expression control sequence comprising a promoter; and a second reporter nucleic acid sequence operably linked to a second expression control sequence that comprises a response element that is activated or inactivated as one or more of the cells differentiate or dedifferentiate. Methods and kits for imaging and monitoring stem cells comprising the expression vector are also provided.