Apparatus and associated methods relate to a dynamic lane-to-lane skew reduction technique having (a) a clocking architecture configured to provide a corresponding first delayed clock signal and a corresponding second delayed clock signal through a first and a second plurality of routing traces, respectively, and (b) a number of skew compensation circuits configured to process the corresponding first delayed clock signal and the corresponding second delayed clock signal to generate a corresponding user clock signal for a corresponding lane of a transmitter. In an illustrative example, a first routing trace may transmit a first delayed clock signal in a direction opposite to a second routing trace transmitting a second delayed clock signal. By implementing the technique, each transmitter lane may receive a corresponding user clock signal having substantially the same delay relative to a reference clock signal such that dynamic lane-to-lane skew may be advantageously reduced.