- 专利标题: Compounds and methods for treating cancer
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申请号: US16575733申请日: 2019-09-19
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公开(公告)号: US10934256B2公开(公告)日: 2021-03-02
- 发明人: James Bradner , Michael Erb , Jun Qi
- 申请人: Dana-Farber Cancer Institute, Inc.
- 申请人地址: US MA Boston
- 专利权人: Dana-Farber Cancer Institute, Inc.
- 当前专利权人: Dana-Farber Cancer Institute, Inc.
- 当前专利权人地址: US MA Boston
- 代理机构: Burns & Levinson, LLP
- 代理商 Daniel W. Clarke
- 主分类号: C07D211/44
- IPC分类号: C07D211/44 ; C07D401/14 ; C07D401/04 ; C07D413/04 ; C07D239/78 ; C07D471/04 ; C07D211/58 ; C07D213/30 ; A61P35/00
摘要:
The present application relates to compounds comprising an ester, a thioester, or a hydrazide moiety and methods of synthesizing these compounds. The present application also relates to pharmaceutical compositions containing the compounds and methods of treating cell proliferative disorders mediated by the Hh signaling pathway, such as cancer, by administering the compounds and pharmaceutical compositions to subjects in need thereof.
公开/授权文献
- US20200010418A1 COMPOUNDS AND METHODS FOR TREATING CANCER 公开/授权日:2020-01-09
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