发明授权
- 专利标题: Transformant, and method for producing protocatechuic acid or salt thereof using same
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申请号: US16089567申请日: 2017-02-24
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公开(公告)号: US10961526B2公开(公告)日: 2021-03-30
- 发明人: Masayuki Inui , Kazumi Hiraga , Masako Suda , Takahisa Kogure
- 申请人: RESEARCH INSTITUTE OF INNOVATIVE TECHNOLOGY FOR THE EARTH , SUMITOMO BAKELITE CO., LTD.
- 申请人地址: JP Kyoto; JP Tokyo
- 专利权人: RESEARCH INSTITUTE OF INNOVATIVE TECHNOLOGY FOR THE EARTH,SUMITOMO BAKELITE CO., LTD.
- 当前专利权人: RESEARCH INSTITUTE OF INNOVATIVE TECHNOLOGY FOR THE EARTH,SUMITOMO BAKELITE CO., LTD.
- 当前专利权人地址: JP Kyoto; JP Tokyo
- 代理机构: Wenderoth, Lind & Ponack, L.L.P.
- 优先权: JP2016-064516 20160328
- 国际申请: PCT/JP2017/007233 WO 20170224
- 国际公布: WO2017/169399 WO 20171005
- 主分类号: C12P7/42
- IPC分类号: C12P7/42 ; C12N9/88 ; C12N15/09 ; C12N1/00 ; C12N9/02 ; C12R1/15
摘要:
Provided is a microorganism that is able to efficiently produce protocatechuic acid or a salt thereof by using a saccharide as a raw material, and a method of efficiently producing protocatechuic acid or a salt thereof by using the microorganism. Provided is a transformant having protocatechuic acid producing ability, subjected to modifications of enhancement of 3-dehydroshikimate dehydratase activity; enhancement of chorismate pyruvate lyase activity; and enhancement of 4-hydroxybenzoate hydroxylase activity. Also provided is a method of producing protocatechuic acid or a salt thereof, including the step of culturing the transformant in a reaction solution containing a saccharide so as to cause the transformant to produce protocatechuic acid or a salt thereof.
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