Invention Grant
- Patent Title: Adeno-associated virus purification methods
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Application No.: US16347082Application Date: 2017-11-03
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Publication No.: US11000561B2Publication Date: 2021-05-11
- Inventor: Christian Fiedler , Leopold Grillberger , Meinhard Hasslacher , Barbara Kraus , Dominik Mittergradnegger , Stefan Reuberger , Horst Schafhauser , Marian Bendik
- Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED
- Applicant Address: JP Osaka
- Assignee: TAKEDA PHARMACEUTICAL COMPANY LIMITED
- Current Assignee: TAKEDA PHARMACEUTICAL COMPANY LIMITED
- Current Assignee Address: JP Osaka
- Agency: Troutman Pepper Hamilton Sanders LLP
- International Application: PCT/US2017/059967 WO 20171103
- International Announcement: WO2018/128688 WO 20180712
- Main IPC: C12N7/02
- IPC: C12N7/02 ; A61K35/761 ; C12N7/00
Abstract:
Provided herein are methods of producing an adeno-associated virus (AAV) product, methods of purifying adeno-associated virus, and methods of purifying full AAV capsids from a concentrated AAV fraction comprising empty AAV capsids and full AAV capsids.
Information query
