Invention Grant
- Patent Title: Site-specific bio-conjugation methods and compositions useful for nanopore systems
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Application No.: US16134179Application Date: 2018-09-18
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Publication No.: US11001611B2Publication Date: 2021-05-11
- Inventor: Dmitriy Gremyachinskiy , Christos Tzitzilonis
- Applicant: Roche Sequencing Solutions, Inc.
- Applicant Address: US CA Pleasanton
- Assignee: Roche Sequencing Solutions, Inc.
- Current Assignee: Roche Sequencing Solutions, Inc.
- Current Assignee Address: US CA Pleasanton
- Agency: FisherBroyles, LLP
- Agent Victoria L. Boyd; Adam Kurt Whiting
- Main IPC: C07K14/315
- IPC: C07K14/315 ; C07K1/107 ; C12Q1/68 ; A61K47/64 ; C07K19/00 ; C12N9/12 ; C12N9/52 ; C12N15/62
Abstract:
The present disclosure relates to relates methods and associated compositions that provide fast, efficient site-selective conjugation of a protein, such as the pore-forming protein α-hemolysin, to a biomolecule, such as a DNA polymerase, and the use of such site-selective protein-biomolecule conjugates in nanopore devices and methods.
Public/Granted literature
- US20190002509A1 SITE-SPECIFIC BIO-CONJUGATION METHODS AND COMPOSITIONS USEFUL FOR NANOPORE SYSTEMS Public/Granted day:2019-01-03
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