Invention Grant
- Patent Title: Alkaline stable Fc-binding proteins for affinity chromatography
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Application No.: US16324842Application Date: 2017-08-07
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Publication No.: US11014967B2Publication Date: 2021-05-25
- Inventor: Paul Knick , Erik Fiedler , Ulrich Haupts , Maren Meysing
- Applicant: Repligen Corporation
- Applicant Address: US MA Waltham
- Assignee: Repligen Corporation
- Current Assignee: Repligen Corporation
- Current Assignee Address: US MA Waltham
- Agency: Kacvinsky Daisak Bluni PLLC
- Priority: EP16183710 20160811,EP16205707 20161221
- International Application: PCT/EP2017/069979 WO 20170807
- International Announcement: WO2018/029158 WO 20180215
- Main IPC: C07K1/22
- IPC: C07K1/22 ; C07K14/31 ; C07K17/00 ; C07K16/06

Abstract:
The present invention relates to Fc binding proteins comprising one or more Fc binding domains wherein at least one domain comprises of an amino acid sequence selected from the group consisting of SEQ ID NOs: 1-6 or 21. The invention further relates to affinity matrices comprising the Fc binding proteins of the invention. The invention also relates to a use of these Fc binding proteins or affinity matrices for affinity purification of immunoglobulins and to methods of affinity purification using the Fc binding proteins of the invention.
Public/Granted literature
- US20190300568A1 ALKALINE STABLE FC-BINDING PROTEINS FOR AFFINITY CHROMATOGRAPHY Public/Granted day:2019-10-03
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