A system for treating tissue includes a clip assembly including a pair of clip arms, proximal ends of which are slidably received within a channel of a capsule to be moved between a tissue receiving configuration, in which distal ends of the clip arms are separated from one another, and a tissue clipping configuration, in which the distal ends are moved toward one another. The system also includes an applicator including a catheter and a control member extending therethrough. The control member configured to be connected to the clip arms to move the clip assembly between the tissue receiving and tissue clipping configurations. The system also includes a coupler attached to one of a proximal end of the capsule of the clip assembly and a distal end of the catheter, and configured to releasably couple the capsule and the catheter to one another.