Invention Grant
- Patent Title: Fused tricyclic pyridazinone compounds useful to treat orthomyxovirus infections
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Application No.: US16328616Application Date: 2017-08-25
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Publication No.: US11098051B2Publication Date: 2021-08-24
- Inventor: Rama Jain , Dennis Christofer Koester , James R. Manning , Vanessa Marx , Daniel Poon , James Clifford Sutton , Benjamin Robert Taft , Lifeng Wan , Aregahegn Yifru , Qian Zhao
- Applicant: Novartis AG
- Applicant Address: CH Basel
- Assignee: Novartis AG
- Current Assignee: Novartis AG
- Current Assignee Address: CH Basel
- Agency: Barnes & Thornburg LLP
- International Application: PCT/IB2017/055137 WO 20170825
- International Announcement: WO2018/042303 WO 20180308
- Main IPC: C07D487/14
- IPC: C07D487/14 ; C07D471/14 ; C07D498/14 ; A61P31/16 ; A61K31/16 ; A61K31/5025 ; A61K31/53 ; A61K31/5365 ; A61K31/5383 ; A61K31/551

Abstract:
The invention provides compounds of Formula (I): as further described herein, as well as pharmaceutical compositions comprising such compounds, and methods to use the compounds and pharmaceutical compositions for treatment of certain viral disorders, including influenza.
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