Invention Grant
- Patent Title: Dimers of covalent NFKB inhibitors
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Application No.: US16471070Application Date: 2017-12-21
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Publication No.: US11104684B2Publication Date: 2021-08-31
- Inventor: Amarnath Natarajan , Sandeep Rana
- Applicant: BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA
- Applicant Address: US NE Lincoln
- Assignee: BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA
- Current Assignee: BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA
- Current Assignee Address: US NE Lincoln
- Agency: Marshall, Gerstein & Borun LLP
- International Application: PCT/US2017/067794 WO 20171221
- International Announcement: WO2018/119177 WO 20180628
- Main IPC: C07D487/10
- IPC: C07D487/10 ; C07D491/107 ; A61P35/00 ; C07D519/00
Abstract:
Provided herein are compounds and methods for modulating the NFκB pathway. More particularly, provided are inhibitors of the NFκB pathway and the uses of such inhibitors in regulating diseases and disorders, e.g., to treat cancer, autoimmune diseases, inflammatory diseases, diabetes, cardiovascular diseases, or neurological diseases.
Public/Granted literature
- US20190322680A1 Dimers of Covalent NFKB Inhibitors Public/Granted day:2019-10-24
Information query
