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    ANTIMICROBIAL COMPOSITIONS CONTAINING A SYNERGISTIC COMBINATION OF ACTIVATED CREATININE AND AN IMIDAZOLE ANTIFUNGAL AGENT
    3.
    发明申请
    ANTIMICROBIAL COMPOSITIONS CONTAINING A SYNERGISTIC COMBINATION OF ACTIVATED CREATININE AND AN IMIDAZOLE ANTIFUNGAL AGENT 有权

    公开(公告)号：US20250017904A1

    公开(公告)日：2025-01-16

    申请号：US18901499

    申请日：2024-09-30

    Applicant: Board of Regents of the University of Nebraska

    Inventor： Thomas McDonald ,  Steven M. Tracy

    IPC: A61K31/4166 ,  A61K9/00 ,  A61K31/4164 ,  A61P31/04 ,  A61P31/10

    Abstract: An antimicrobial composition containing a synergistic combination of an imidazole antifungal agent and activated creatinine is provided, wherein the imidazole antifungal agent represents in the range of about 0.5 mol % to about 30 mol % of the combination of the antifungal agent and the activated creatinine in the composition. Methods for treating bacterial infections, fungal infections, viral infections, and wounds are also provided, as are other methods of use, including methods for disinfecting inert surfaces, methods for preserving food products, and methods for treating plants. In addition, the invention provides a method for enhancing the antifungal effect of an imidazole antifungal agent as well as a method for enhancing the antibacterial effect of activated creatinine. Compositions and methods involving use of activated 2-amino-imidazol-4-one analogs other than activated creatinine are also provided.

    Camera aided simulator for minimally invasive surgical training
    6.
    发明授权
    Camera aided simulator for minimally invasive surgical training 有权

    公开(公告)号：US12154455B2

    公开(公告)日：2024-11-26

    申请号：US17746100

    申请日：2022-05-17

    Applicant: Board of Regents of the University of Nebraska

    Inventor： Ka-Chun Siu ,  Carl Nelson ,  Mohsen Zahiri ,  Dmitry Oleynikov

    IPC: G09B23/28 ,  G09B9/00 ,  G09B23/24 ,  G09B19/24

    Abstract: The present disclosure is directed to a system and method for surgical training with low cost, reusable materials and a highly customizable virtual environment for skill-building. According to various embodiments, a surgical training tool is usable in conjunction with a support structure configured to at least partially constrain the tool movement. Meanwhile, the tool is tracked in real-time with off-tool detectors to generate a tool path driving a virtual rendering of the surgical training tool in an operative environment. The virtual rendering may be visually observable via a display device and may include a customizable and/or selectable operative environment with one or more structures that can be operated on by the virtual surgical training tool. By tracking the virtual tool interaction with the virtual structures, a task path may be established for documenting and/or objectively assessing the performance of one or more operative tasks.

    Automatically deployable intravascular device system
    7.
    发明授权
    Automatically deployable intravascular device system 有权

    公开(公告)号：US12138186B2

    公开(公告)日：2024-11-12

    申请号：US17258100

    申请日：2019-07-03

    Applicant: Board of Regents of the University of Nebraska

    Inventor： Jason N. MacTaggart ,  Alexey Kamenskiy ,  Blake Marmie

    IPC: A61F2/958 ,  A61B8/00 ,  A61B8/08 ,  A61B8/12

    Abstract: This document describes devices, systems, and methods for automatically deploying intravascular devices. For example, this document describes devices, systems, and methods for automatically deploying and controlling intravascular catheter-based devices for treating catastrophic bleeding from large and medium size vessels such as, but not limited to, the aorta or iliac arteries. In some embodiments, an operator/care giver will simply press the system against the patient's body proximate to a desired site of insertion, or will attach the system to the patient proximate to the desired site of insertion. The operator will then activate the system. Thereafter, the system will use built in imaging (e.g., ultrasound) to locate a proper insertion point and then deploy an access needle to attain vascular access. With that, the system will then automatically insert the intravascular device into the patient.

    Apparatus for wrist and catheter stabilization
    8.
    外观设计
    Apparatus for wrist and catheter stabilization 有权

    公开(公告)号：USD1046125S1

    公开(公告)日：2024-10-08

    申请号：US29867207

    申请日：2022-10-14

    Applicant: Board of Regents of the University of Nebraska

    Designer： Carlos Alvarez ,  William Thorell ,  Daniel Surdell ,  Andrew Gard ,  Landon Ehlers

    Abstract: FIG. 1 is a left side perspective view of an apparatus for wrist and catheter stabilization;
    FIG. 2 is a right side perspective view of the apparatus for wrist and catheter stabilization of FIG. 1;
    FIG. 3 is a left side elevation view of the apparatus for wrist and catheter stabilization of FIG. 1;
    FIG. 4 is a right side elevation view of the apparatus for wrist and catheter stabilization of FIG. 1;
    FIG. 5 is a rear end elevation view of the apparatus for wrist and catheter stabilization of FIG. 1;
    FIG. 6 is a front end elevation view of the apparatus for wrist and catheter stabilization of FIG. 1;
    FIG. 7 is a bottom view of the apparatus for wrist and catheter stabilization of FIG. 1; and,
    FIG. 8 is a top view of the apparatus for wrist and catheter stabilization of FIG. 1.
    Broken lines in the drawings illustrate portions of the apparatus for wrist and catheter stabilization that form no part of the claimed design.

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