Invention Grant
- Patent Title: Tetrahydroquinoline compositions as BET bromodomain inhibitors
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Application No.: US16774515Application Date: 2020-01-28
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Publication No.: US11111229B2Publication Date: 2021-09-07
- Inventor: Kenneth W. Bair , Torsten Herbertz , Goss S. Kauffman , Katherine J. Kayser-Bricker , George P. Luke , Matthew W. Martin , David S. Millan , Shawn E. R. Schiller , Adam C. Talbot
- Applicant: FORMA Therapeutics, Inc.
- Applicant Address: US MA Watertown
- Assignee: FORMA Therapeutics, Inc.
- Current Assignee: FORMA Therapeutics, Inc.
- Current Assignee Address: US MA Watertown
- Agency: Choate, Hall & Stewart LLP
- Agent Michael A. Shinall; Erica M. D'Amato
- Main IPC: C07D401/04
- IPC: C07D401/04 ; C07D401/14 ; A61K31/4709 ; A61K45/06 ; A61K31/47 ; A61K31/497 ; A61K31/506 ; A61K31/5377 ; C07D405/14 ; C07D413/14 ; C07D215/20 ; C07D215/48 ; C07D409/14 ; C07D413/04 ; C07D417/04 ; C07D417/14 ; C07D471/04 ; C07D473/28 ; C07D487/04 ; A61K31/517 ; A61K31/519 ; A61K31/496 ; A61K31/501 ; A61K31/52 ; C07D401/12 ; C07D405/04 ; C07D417/10
Abstract:
The present invention relates to inhibitors of bromo and extra terminal (BET) bromodomains that are useful for the treatment of cancer, inflammatory diseases, diabetes, and obesity, having Formula I: wherein W, X, Y, Z, R1, R2, R5, and R8 are as described herein.
Public/Granted literature
- US20200369642A1 TETRAHYDROQUINOLINE COMPOSITIONS AS BET BROMODOMAIN INHIBITORS Public/Granted day:2020-11-26
Information query
