-
公开(公告)号：US20190330233A1
公开(公告)日：2019-10-31
申请号：US16444032
申请日：2019-06-18
Applicant: FORMA Therapeutics, Inc.
Inventor： Kenneth W. Bair , Torsten Herbertz , Goss S. Kauffman , Katherine J. Kayser-Bricker , George P. Luke , Matthew W. Martin , David S. Millan , Shawn E.R. Schiller , Adam C. Talbot , Mark J. Tebbe
IPC: C07D498/04 , A61K31/553 , C07D401/14 , A61K31/506 , A61K31/517 , A61K31/551 , A61K31/541 , A61K31/5377 , A61K31/519 , A61K31/5025 , C07D495/04 , C07D491/048 , C07D487/08 , C07D487/04 , C07D471/04 , C07D451/04 , C07D241/50 , C07D417/06 , C07D417/04 , C07D413/12 , C07D413/06 , C07D409/12 , C07D409/06 , C07D405/12 , C07D405/10 , C07D405/04 , C07D403/06 , C07D401/12 , C07D401/10 , C07D401/06 , A61K31/53 , C07D403/12 , A61K31/498 , A61K45/06 , C07D417/14 , C07D417/10 , C07D241/42 , C07D413/04 , C07D409/14 , C07D405/06 , C07D403/14 , C07D403/10 , C07D403/04 , C07D401/04 , A61K31/4985 , C07D413/14 , C07D405/14 , A61K31/55
Abstract: The present invention relates to inhibitors of bromo and extra terminal (BET) bromodomains that are useful for the treatment of cancer, inflammatory diseases, diabetes, and obesity, having Formula (I): wherein X, Y, Z, R1, R2, R4 and R7 are defined herein.
-
公开(公告)号：US11111229B2
公开(公告)日：2021-09-07
申请号：US16774515
申请日：2020-01-28
Applicant: FORMA Therapeutics, Inc.
Inventor： Kenneth W. Bair , Torsten Herbertz , Goss S. Kauffman , Katherine J. Kayser-Bricker , George P. Luke , Matthew W. Martin , David S. Millan , Shawn E. R. Schiller , Adam C. Talbot
IPC: C07D401/04 , C07D401/14 , A61K31/4709 , A61K45/06 , A61K31/47 , A61K31/497 , A61K31/506 , A61K31/5377 , C07D405/14 , C07D413/14 , C07D215/20 , C07D215/48 , C07D409/14 , C07D413/04 , C07D417/04 , C07D417/14 , C07D471/04 , C07D473/28 , C07D487/04 , A61K31/517 , A61K31/519 , A61K31/496 , A61K31/501 , A61K31/52 , C07D401/12 , C07D405/04 , C07D417/10
Abstract: The present invention relates to inhibitors of bromo and extra terminal (BET) bromodomains that are useful for the treatment of cancer, inflammatory diseases, diabetes, and obesity, having Formula I: wherein W, X, Y, Z, R1, R2, R5, and R8 are as described herein.
-
公开(公告)号：US20200369642A1
公开(公告)日：2020-11-26
申请号：US16774515
申请日：2020-01-28
Applicant: FORMA Therapeutics, Inc.
Inventor： Kenneth W. Bair , Torsten Herbertz , Goss S. Kauffman , Katherine J. Kayser-Bricker , George P. Luke , Matthew W. Martin , David S. Millan , Shawn E.R. Schiller , Adam C. Talbot
IPC: C07D401/04 , C07D401/14 , A61K31/4709 , A61K45/06 , A61K31/47 , A61K31/497 , A61K31/506 , A61K31/5377 , C07D405/14 , C07D413/14 , C07D215/20 , C07D215/48 , C07D409/14 , C07D413/04 , C07D417/04 , C07D417/14 , C07D471/04 , C07D473/28 , C07D487/04 , A61K31/517 , A61K31/519 , A61K31/496 , A61K31/501 , A61K31/52 , C07D401/12 , C07D405/04 , C07D417/10
Abstract: The present invention relates to inhibitors of bromo and extra terminal (BET) bromodomains that are useful for the treatment of cancer, inflammatory diseases, diabetes, and obesity, having Formula I: wherein W, X, Y, Z, R1, R2, R5, and R8 are as described herein.
-
公开(公告)号：US10377769B2
公开(公告)日：2019-08-13
申请号：US16029166
申请日：2018-07-06
Applicant: FORMA Therapeutics, Inc.
Inventor： Kenneth W. Bair , Torsten Herbertz , Goss S. Kauffman , Katherine J. Kayser-Bricker , George P. Luke , Matthew W. Martin , David S. Millan , Shawn E. R. Schiller , Adam C. Talbot , Mark J. Tebbe
IPC: C07D498/04 , C07D403/12 , C07D401/14 , C07D405/14 , C07D413/14 , A61K31/4985 , A61K31/53 , C07D401/04 , C07D401/06 , C07D401/10 , C07D401/12 , C07D403/04 , C07D403/06 , C07D403/10 , C07D403/14 , C07D405/04 , C07D405/06 , C07D405/10 , C07D405/12 , C07D409/06 , C07D409/12 , C07D409/14 , C07D413/04 , C07D413/06 , C07D413/12 , C07D417/04 , C07D417/06 , C07D241/42 , C07D417/10 , C07D241/50 , C07D417/14 , C07D451/04 , C07D471/04 , C07D487/04 , C07D487/08 , C07D491/048 , C07D495/04 , A61K45/06 , A61K31/498 , A61K31/5025 , A61K31/519 , A61K31/5377 , A61K31/541 , A61K31/551 , A61K31/506 , A61K31/517 , A61K31/55 , A61K31/553
Abstract: The present invention relates to inhibitors of bromo and extra terminal (BET) bromodomains that are useful for the treatment of cancer, inflammatory diseases, diabetes, and obesity, having Formula (I): wherein X, Y, Z, R1, R2, R4 and R7 are defined herein.
-
公开(公告)号：US20230061891A1
公开(公告)日：2023-03-02
申请号：US17383610
申请日：2021-07-23
Applicant: FORMA Therapeutics, Inc.
Inventor： Kenneth W. Bair , Torsten Herbertz , Goss S. Kauffman , Katherine J. Kayser-Bricker , George P. Luke , Matthew W. Martin , David S. Millan , Shawn E.R. Schiller , Adam C. Talbot
IPC: C07D401/04 , C07D401/14 , A61K31/4709 , A61K45/06 , A61K31/47 , A61K31/497 , A61K31/506 , A61K31/5377 , C07D405/14 , C07D413/14 , C07D215/20 , C07D215/48 , C07D409/14 , C07D413/04 , C07D417/04 , C07D417/14 , C07D471/04 , C07D473/28 , C07D487/04 , A61K31/517 , A61K31/519 , A61K31/496 , A61K31/501 , A61K31/52 , C07D401/12 , C07D405/04 , C07D417/10
Abstract: The present invention relates to inhibitors of bromo and extra terminal (BET) bromodomains that are useful for the treatment of cancer, inflammatory diseases, diabetes, and obesity, having Formula I: wherein W, X, Y, Z, R1, R2, R5, and R8 are as described herein.
-
Patent Agency Ranking
公开(公告)号：US20190127347A1
公开(公告)日：2019-05-02
申请号：US16225484
申请日：2018-12-19
Applicant: FORMA Therapeutics, Inc.
Inventor： Kenneth W. Bair , Torsten Herbertz , Goss S. Kauffman , Katherine J. Kayser-Bricker , George P. Luke , Matthew W. Martin , David S. Millan , Shawn E.R. Schiller , Adam C. Talbot
IPC: C07D401/04 , C07D487/04 , A61K45/06 , A61K31/52 , C07D401/12 , C07D405/04 , A61K31/496 , A61K31/501 , C07D417/14 , C07D417/04 , C07D413/04 , C07D409/14 , C07D215/48 , C07D215/20 , C07D413/14 , C07D405/14 , C07D473/28 , C07D471/04 , A61K31/519 , A61K31/517 , A61K31/4709 , C07D401/14 , A61K31/5377 , A61K31/506 , A61K31/497 , A61K31/47 , C07D417/10
Abstract: The present invention relates to inhibitors of bromo and extra terminal (BET) bromodomains that are useful for the treatment of cancer, inflammatory diseases, diabetes, and obesity, having Formula I: wherein W, X, Y, Z, R1, R2, R5, and R8 are as described herein.
-
公开(公告)号：US20180312524A1
公开(公告)日：2018-11-01
申请号：US16029166
申请日：2018-07-06
Applicant: FORMA Therapeutics, Inc.
Inventor： Kenneth W. Bair , Torsten Herbertz , Goss S. Kauffman , Katherine J. Kayser-Bricker , George P. Luke , Matthew W. Martin , David S. Millan , Shawn E.R. Schiller , Adam C. Talbot , Mark J. Tebbe
IPC: C07D498/04 , C07D413/14 , C07D409/12 , C07D241/50 , A61K31/541 , C07D403/10 , A61K31/517 , A61K31/55 , C07D417/06 , C07D401/14 , C07D417/10 , C07D405/14 , C07D401/12 , C07D487/04 , C07D413/12 , A61K31/553 , C07D487/08 , C07D491/048 , C07D417/04 , C07D413/04 , C07D401/10 , A61K31/519 , C07D409/06 , A61K31/506 , A61K31/5025 , A61K31/53 , C07D471/04 , C07D403/06 , C07D417/14 , A61K31/4985 , C07D413/06 , A61K31/551 , C07D451/04 , A61K31/498 , C07D405/10 , C07D401/04 , C07D241/42 , A61K31/5377 , C07D409/14 , C07D403/04 , C07D403/14 , C07D401/06 , C07D405/12 , C07D403/12 , C07D405/06 , A61K45/06 , C07D495/04 , C07D405/04
CPC classification number: C07D498/04 , A61K31/498 , A61K31/4985 , A61K31/5025 , A61K31/506 , A61K31/517 , A61K31/519 , A61K31/53 , A61K31/5377 , A61K31/541 , A61K31/55 , A61K31/551 , A61K31/553 , A61K45/06 , C07D241/42 , C07D241/50 , C07D401/04 , C07D401/06 , C07D401/10 , C07D401/12 , C07D401/14 , C07D403/04 , C07D403/06 , C07D403/10 , C07D403/12 , C07D403/14 , C07D405/04 , C07D405/06 , C07D405/10 , C07D405/12 , C07D405/14 , C07D409/06 , C07D409/12 , C07D409/14 , C07D413/04 , C07D413/06 , C07D413/12 , C07D413/14 , C07D417/04 , C07D417/06 , C07D417/10 , C07D417/14 , C07D451/04 , C07D471/04 , C07D487/04 , C07D487/08 , C07D491/048 , C07D495/04 , A61K2300/00
Abstract: The present invention relates to inhibitors of bromo and extra terminal (BET) bromodomains that are useful for the treatment of cancer, inflammatory diseases, diabetes, and obesity, having Formula (I): wherein X, Y, Z, R1, R2, R4 and R7 are defined herein.
-
公开(公告)号：US20180215766A1
公开(公告)日：2018-08-02
申请号：US15937271
申请日：2018-03-27
Applicant: FORMA Therapeutics, Inc.
Inventor： Kenneth W. Bair , Torsten Herbertz , Goss S. Kauffman , Katherine J. Kayser-Bricker , George P. Luke , Matthew W. Martin , David S. Millan , Shawn E.R. Schiller , Adam C. Talbot
IPC: C07D487/04 , C07D417/10 , A61K31/52 , A61K45/06 , A61K31/47 , A61K31/497 , A61K31/506 , A61K31/5377 , C07D401/14 , A61K31/4709 , A61K31/517 , A61K31/519 , C07D401/12 , C07D405/04 , A61K31/496 , A61K31/501 , C07D417/14 , C07D417/04 , C07D413/04 , C07D409/14 , C07D401/04 , C07D215/48 , C07D215/20 , C07D413/14 , C07D405/14 , C07D473/28 , C07D471/04
CPC classification number: C07D401/04 , A61K31/47 , A61K31/4709 , A61K31/496 , A61K31/497 , A61K31/501 , A61K31/506 , A61K31/517 , A61K31/519 , A61K31/52 , A61K31/5377 , A61K45/06 , C07D215/20 , C07D215/48 , C07D401/12 , C07D401/14 , C07D405/04 , C07D405/14 , C07D409/14 , C07D413/04 , C07D413/14 , C07D417/04 , C07D417/10 , C07D417/14 , C07D471/04 , C07D473/28 , C07D487/04 , A61K2300/00
Abstract: The present invention relates to inhibitors of bromo and extra terminal (BET) bromodomains that are useful for the treatment of cancer, inflammatory diseases, diabetes, and obesity, having Formula I: wherein W, X, Y, Z, R1, R2, R5, and R8 are as described herein.
-
公开(公告)号：US09388161B2
公开(公告)日：2016-07-12
申请号：US14546775
申请日：2014-11-18
Applicant: Forma Therapeutics, Inc.
Inventor： Kenneth W. Bair , Torsten Herbertz , Goss S. Kauffman , Katherine J. Kayser-Bricker , George P. Luke , Matthew W. Martin , David S. Millan , Shawn E. R. Schiller , Adam C. Talbot
IPC: C07D401/14 , A61K31/4709 , C07D401/04 , A61K31/5377 , A61K31/517 , C07D487/04 , A61K31/519 , A61K45/06
CPC classification number: C07D487/04 , A61K31/47 , A61K31/4709 , A61K31/496 , A61K31/497 , A61K31/501 , A61K31/506 , A61K31/517 , A61K31/519 , A61K31/52 , A61K31/5377 , A61K45/06 , C07D215/20 , C07D215/48 , C07D401/04 , C07D401/12 , C07D401/14 , C07D405/04 , C07D405/14 , C07D409/14 , C07D413/04 , C07D413/14 , C07D417/04 , C07D417/10 , C07D417/14 , C07D471/04 , C07D473/28 , A61K2300/00
Abstract: The present invention relates to inhibitors of bromo and extra terminal (BET) bromodomains that are useful for the treatment of cancer, inflammatory diseases, diabetes, and obesity, having Formula I: wherein W, X, Y, Z, R1, R2, R5, and R8 are as described herein.
Abstract translation: 本发明涉及可用于治疗癌症，炎性疾病，糖尿病和肥胖症的溴和额外末端（BET）溴结构域的抑制剂，其具有式I：其中W，X，Y，Z，R 1，R 2，R 5 ，和R8如本文所述。
-
公开(公告)号：US11084831B1
公开(公告)日：2021-08-10
申请号：US16872743
申请日：2020-05-12
Applicant: FORMA Therapeutics, Inc.
Inventor： Kenneth W. Bair , Torsten Herbertz , Goss S. Kauffman , Katherine J. Kayser-Bricker , George P. Luke , Matthew W. Martin , David S. Millan , Shawn E. R. Schiller , Adam C. Talbot , Mark J. Tebbe
IPC: C07D498/04 , A61K31/553 , C07D401/14 , C07D405/14 , C07D413/14 , A61K31/4985 , A61K31/53 , C07D401/04 , C07D401/06 , C07D401/10 , C07D401/12 , C07D403/04 , C07D403/06 , C07D403/10 , C07D403/14 , C07D405/04 , C07D405/06 , C07D405/10 , C07D405/12 , C07D409/06 , C07D409/12 , C07D409/14 , C07D413/04 , C07D413/06 , C07D413/12 , C07D417/04 , C07D417/06 , C07D241/42 , C07D417/10 , C07D241/50 , C07D417/14 , C07D451/04 , C07D487/04 , C07D487/08 , C07D491/048 , C07D495/04 , A61K45/06 , A61K31/498 , A61K31/5025 , A61K31/519 , C07D471/04 , A61K31/5377 , A61K31/541 , A61K31/551 , A61K31/506 , A61K31/517 , A61K31/55 , C07D403/12
Abstract: The present invention relates to inhibitors of bromo and extra terminal (BET) bromodomains that are useful for the treatment of cancer, inflammatory diseases, diabetes, and obesity, having Formula (I): wherein X, Y, Z, R1, R2, R4 and R7 are defined herein.
-
-
-
-
-
-
-
-
-
Search Results
13
records
(took 0.067 seconds)
