Invention Grant
- Patent Title: Nuclear transport modulators and uses thereof
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Application No.: US16519955Application Date: 2019-07-23
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Publication No.: US11124493B2Publication Date: 2021-09-21
- Inventor: Erkan Baloglu , Sharon Shacham , Dilara McCauley , Trinayan Kashyap , William Senapedis , Yosef Landesman , Gali Golan , Ori Kalid , Sharon Shechter
- Applicant: Karyopharm Therapeutics Inc.
- Applicant Address: US MA Newton
- Assignee: Karyopharm Therapeutics Inc.
- Current Assignee: Karyopharm Therapeutics Inc.
- Current Assignee Address: US MA Newton
- Agency: Foley Hoag LLP
- Main IPC: A61K31/506
- IPC: A61K31/506 ; A61P35/00 ; C07D403/06 ; C07D401/06 ; C07D249/08 ; C07D405/06 ; C07D413/06 ; C07D417/06

Abstract:
The present invention relates to compounds of formula I: and pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising the compounds of formula I or their pharmaceutically acceptable salts, and methods of using said compounds, salts and compositions in the treatment of various disorders associated with CRM1 activity.
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