Invention Grant
- Patent Title: Multimeric coding nucleic acid and uses thereof
-
Application No.: US16540791Application Date: 2019-08-14
-
Publication No.: US11124804B2Publication Date: 2021-09-21
- Inventor: Frank DeRosa , Michael Heartlein , Daniel Crawford , Shrirang Karve
- Applicant: Translate Bio, Inc.
- Applicant Address: US MA Lexington
- Assignee: Translate Bio, Inc.
- Current Assignee: Translate Bio, Inc.
- Current Assignee Address: US MA Lexington
- Agency: Proskauer Rose LLP
- Agent Fangli Chen
- Main IPC: C07H21/02
- IPC: C07H21/02 ; A61K31/7115 ; A61K31/7125 ; C12N15/85 ; C07K14/505 ; C12N9/10 ; C12N9/02 ; C07K14/705 ; A61K48/00 ; A61K38/17 ; A61K38/44 ; A61K38/45 ; A61K38/18 ; C12N15/67 ; C12P21/00 ; A01K67/00
Abstract:
The present invention provides, among other things, multimeric coding nucleic acids that exhibit superior stability for in vivo and in vitro use. In some embodiments, a multimeric coding nucleic acid (MCNA) comprises two or more encoding polynucleotides linked via 3′ ends such that the multimeric coding nucleic acid compound comprises two or more 5′ ends.
Public/Granted literature
- US20200172923A1 MULTIMERIC CODING NUCLEIC ACID AND USES THEREOF Public/Granted day:2020-06-04
Information query
