Disclosed herein is a technique for managing I/O requests transmitted between a computing device and a storage device. According to some embodiments, the technique can be implemented by the computing device, and include providing at least one I/O request to a submission queue configured to store a plurality of I/O requests. In conjunction with providing the at least one I/O request, the computing device can identify that at least one condition associated with the submission queue—and/or a completion queue—is satisfied, where efficiency gains can be achieved. In turn, the computing device can (1) update an operating mode of the storage device to cause the storage device to cease interrupt issuances to the computing device when I/O requests are completed by the storage device, and (2) update an operating mode of the computing device to cause the computing device to periodically check the completion queue for completed I/O requests.