Embodiments of the present disclosure provide a method for driving a display device to display an image sequence and a display device therefor. The display device includes a backlight module having a plurality of backlight partitions. The image sequence includes at least a first frame image and a second frame image. The method includes determining a first region in the first frame image and a second region in the second frame image that correspond to an overlapping portion of the first frame image and second frame image as overlapping regions; obtaining, based at least partially on a first backlight value of a first backlight partition(s) corresponding to the first region, a second backlight value of a second backlight partition corresponding to the second region; and controlling a backlight brightness of the second backlight partition based on the second backlight value when the display device displays the second frame image.