Invention Grant
- Patent Title: Purinones as ubiquitin-specific protease 1 inhibitors
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Application No.: US16540327Application Date: 2019-08-14
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Publication No.: US11161848B2Publication Date: 2021-11-02
- Inventor: Alexandre Joseph Buckmelter , Stephanos Ioannidis , Bruce Follows , Gary Gustafson , Minghua Wang , Justin A. Caravella , Zhongguo Wang , Edward L. Fritzen , Jian Lin
- Applicant: FORMA Therapeutics, Inc.
- Applicant Address: US MA Watertown
- Assignee: FORMA Therapeutics, Inc.
- Current Assignee: FORMA Therapeutics, Inc.
- Current Assignee Address: US MA Watertown
- Agency: Choate, Hall & Stewart LLP
- Agent John P. Rearick; Nicholas J. Pace
- Main IPC: C07D473/00
- IPC: C07D473/00 ; A61K31/522
Abstract:
The application relates to inhibitors of USP1 useful in the treatment of cancers, and other USP1 associated diseases and disorders, having the Formula: where R1, R2, R3, R3′, R4, R5, X1, X2, X3, X4, and n are described herein.
Public/Granted literature
- US20200079776A1 PURINONES AS UBIQUITIN-SPECIFIC PROTEASE 1 INHIBITORS Public/Granted day:2020-03-12
Information query
IPC分类:
| C | 化学；冶金 |
| C07 | 有机化学 |
| C07D | 杂环化合物（高分子化合物入C08） |
| C07D473/00 | 含嘌呤环系的杂环化合物 |
