Technologies for secure I/O include a compute device having a processor, a memory, an input/output (I/O) device, and a filter logic. The filter logic is configured to receive a first key identifier from the processor, wherein the first key identifier is indicative of a shared memory range includes a shared key identifier range to be used for untrusted I/O devices and receive a transaction from the I/O device, wherein the transaction includes a second key identifier and a trust device ID indicator associated with the I/O device. The filter logic is further configured to determine whether the transaction is asserted with the trust device ID indicator indicative of whether the I/O device is assigned to a trust domain and determine, in response to a determination that the transaction is not asserted with the trust device ID indicator, whether the second key identifier matches the first key identifier.