A pipetting system having at least one pipette tip receptacle with a pipette tip arranged therein that extends along a vertical axis and at least one gripper having a mechanical coupling, the gripper is coupled to the at least one pipette tip receptacle with the coupling and at least one grip element. The at least one grip element has at least one substantially vertical portion and at least one substantially horizontal portion and the coupling has a body having a through channel that extends along the vertical axis over the entire length of the coupling and the pipette tip extends along the through channel of the coupling.