Technical solutions are described for a load-store unit (LSU) that executes a plurality of instructions in an out-of-order (OoO) window using multiple LSU pipes. The execution includes selecting an instruction from the OoO window, the instruction using an effective address; and if the instruction is a load instruction: and if the processing unit is operating in single thread mode, creating an entry in a first partition of a load reorder queue (LRQ) if the instruction is issued on a first load pipe, and creating the entry in a second partition of the LRQ if the instruction is issued on a second load pipe. Further, if the processing unit is operating in a multi-thread mode, creating the entry in a first predetermined portion of the first partition of the LRQ if the instruction is issued on the first load pipe and by a first thread of the processing unit.