This disclosure describes systems, methods, and devices related to using enhanced acknowledgment and power save. A device may determine a multi-user (MU) multiple-input multiple-output (MIMO) frame associated with a MU-MIMO group. The device may determine a first portion of the MU-MIMO frame associated with the first station device of the MU-MIMO group, wherein the first portion comprises a first indication of a first time offset associated with the first station device. The device may determine a second portion of the MU-MIMO frame associated with the second station device of the MU-MIMO group, wherein the second portion comprises a second indication of a second time offset associated with the second station device. The device may cause to send the MU-MIMO frame to the MU-MIMO group. The device may identify a first acknowledgment from the first station device based on the first time offset.