- 专利标题： Phosphonamide ester compound, salt thereof, related crystal form thereof, preparation method therefor and use thereof
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申请号： US17047000申请日： 2019-06-03
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公开(公告)号： US11186599B2公开(公告)日： 2021-11-30
- 发明人: Qiang Tian , Tianming Wang , Wei Liu , Baolei Zhang , Mingliang Zhao , Yufeng Liang , Jiaqiang Cai , Lichun Wang , Jingyi Wang
- 申请人： SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD.
- 申请人地址： CN Chengdu
- 专利权人： SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD.
- 当前专利权人： SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD.
- 当前专利权人地址： CN Chengdu
- 代理机构： Kilpatrick Townsend & Stockton LLP
- 优先权： CN201810600569.X 20180612
- 国际申请： PCT/CN2019/089744 WO 20190603
- 国际公布： WO2019/237957 WO 20191219
- 主分类号： C07F9/6561
- IPC分类号： C07F9/6561 ; C07F9/02
摘要：
The present invention relates to compounds represented by formula (I) and formula (II) and a chiral synthesis and chiral isolation method therefor, further relating to a salt and crystal form of the compound represented by formula (I), a preparation method therefor, a pharmaceutical composition comprising the same, and use thereof in the preparation of a medicament used for the treatment of a viral infectious disease such as hepatitis B.
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