Invention Grant
- Patent Title: Intermediates useful for the synthesis of a selective inhibitor against protein kinase and processes for preparing the same
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Application No.: US16633756Application Date: 2018-07-25
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Publication No.: US11198684B2Publication Date: 2021-12-14
- Inventor: Sang-Ho Oh , Ja-Heouk Khoo , Jong-Chul Lim , Doo-Byung Lee , Jung-Ae Lee , Jun-Sup Lee , Hyun Ju , Woo-Seob Shin , Sang-Seol Jeon
- Applicant: Yuhan Corporation
- Applicant Address: KR Seoul
- Assignee: Yuhan Corporation
- Current Assignee: Yuhan Corporation
- Current Assignee Address: KR Seoul
- Agency: BakerHostetler
- Priority: KR10-2017-0096226 20170728
- International Application: PCT/KR2018/008383 WO 20180725
- International Announcement: WO2019/022487 WO 20190131
- Main IPC: C07D265/30
- IPC: C07D265/30 ; C07D295/135 ; C07D403/04 ; C07D413/14

Abstract:
The present invention provides intermediates useful for the synthesis of an aminopyrimidine derivative or pharmaceutically acceptable salt thereof having a selective inhibitory activity against protein kinases, especially against the protein kinases for mutant epidermal growth factor receptors; and processes for preparing the same. And also, the present invention provides novel intermediates useful for said process and processes for preparing the same.
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