专利检索 ap:("Yuhan Corporation") AND inv:"Jung-Ae Lee" 第 1 页

1.

发明授权
Intermediates useful for the synthesis of a selective inhibitor against protein kinase and processes for preparing the same 有权

公开(公告)号：US11198684B2

公开(公告)日：2021-12-14

申请号：US16633756

申请日：2018-07-25

申请人： Yuhan Corporation

发明人： Sang-Ho Oh , Ja-Heouk Khoo , Jong-Chul Lim , Doo-Byung Lee , Jung-Ae Lee , Jun-Sup Lee , Hyun Ju , Woo-Seob Shin , Sang-Seol Jeon

IPC分类号： C07D265/30 , C07D295/135 , C07D403/04 , C07D413/14

摘要： The present invention provides intermediates useful for the synthesis of an aminopyrimidine derivative or pharmaceutically acceptable salt thereof having a selective inhibitory activity against protein kinases, especially against the protein kinases for mutant epidermal growth factor receptors; and processes for preparing the same. And also, the present invention provides novel intermediates useful for said process and processes for preparing the same.

2.

发明授权
Intermediates useful for the synthesis of aminopyrimidine derivatives, process for preparing the same, and process for preparing aminopyrimidine derivatives using the same 有权

公开(公告)号：US10858353B2

公开(公告)日：2020-12-08

申请号：US16633695

申请日：2018-07-25

申请人： Yuhan Corporation

发明人： Sang-Ho Oh , Ja-Heouk Khoo , Jong-Chul Lim , Doo-Byung Lee , Jung-Ae Lee , Jun-Sup Lee , Hyun Ju , Woo-Seob Shin , Sang-Seol Jeon

IPC分类号： C07D413/14 , C07D265/32 , C07D403/10

摘要： The present invention provides a novel process for preparing an aminopyrimidine derivative or pharmaceutically acceptable salt thereof having a selective inhibitory activity against protein kinases, especially against the protein kinases for mutant epidermal growth factor receptors. And also, the present invention provides novel intermediates useful for said process and processes for preparing the same.