Invention Grant
- Patent Title: Humanised anti kallikrein-2 antibody
-
Application No.: US16117522Application Date: 2018-08-30
-
Publication No.: US11230609B2Publication Date: 2022-01-25
- Inventor: Par Oskar Vilhelmsson Timmermand , Amanda Thuy Tran , Sven-Erik Strand , Urpo Juhani Lamminmaki , Kjell Sjostrom
- Applicant: JANSSEN BIOTECH, INC.
- Applicant Address: US PA Horsham
- Assignee: JANSSEN BIOTECH, INC.
- Current Assignee: JANSSEN BIOTECH, INC.
- Current Assignee Address: US PA Horsham
- Agency: BakerHostetler
- Priority: GB1320408 20131119,GB1401973 20140205
- Main IPC: C07K16/40
- IPC: C07K16/40 ; C07K16/30 ; A61K51/10 ; A61K39/00
Abstract:
The present invention provides antibody polypeptides with binding specificity for human kallikrein-2 (hK2), wherein the antibody polypeptide comprises (a) a heavy chain variable region comprising the amino acid sequences of SEQ ID NO:1 and SEQ ID NO:2 and SEQ ID NO:3 and/or (b) a light chain variable region comprising the amino acid sequences of SEQ ID NO:4 and SEQ ID NO:5 and SEQ ID NO:6, and wherein the heavy chain variable region and light chain variable region comprise framework amino acid sequences from one or more human antibodies. The invention further provides use of said antibody polypeptides in the diagnosis and treatment of prostate cancer.
Public/Granted literature
- US20190169312A1 HUMANISED ANTI KALLIKREIN-2 ANTIBODY Public/Granted day:2019-06-06
Information query
