- 专利标题： Gene involved in synthesis of cyclic peptide compound, method for producing cyclic peptide compound using the same, and transformant comprising the same
-
申请号： US16476000申请日： 2017-12-27
-
公开(公告)号： US11230726B2公开(公告)日： 2022-01-25
- 发明人: Takashi Kubo , Masayuki Machida , Maiko Umemura , Keietsu Abe , Akira Yoshimi , Tomonori Fujioka , Shigenari Yamaguchi , Kiyoshi Kawai
- 申请人： NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY , TOHOKU UNIVERSITY , KUMIAI CHEMICAL INDUSTRY CO., LTD.
- 申请人地址： JP Tokyo; JP Sendai; JP Tokyo
- 专利权人： NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY,TOHOKU UNIVERSITY,KUMIAI CHEMICAL INDUSTRY CO., LTD.
- 当前专利权人： NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY,TOHOKU UNIVERSITY,KUMIAI CHEMICAL INDUSTRY CO., LTD.
- 当前专利权人地址： JP Tokyo; JP Sendai; JP Tokyo
- 代理机构： Birch, Stewart, Kolasch & Birch, LLP
- 优先权： JPJP2017-000770 20170105
- 国际申请： PCT/JP2017/046858 WO 20171227
- 国际公布： WO2018/128140 WO 20180712
- 主分类号： C12N1/16
- IPC分类号： C12N1/16 ; C12N1/20 ; C12P21/04 ; C12P21/02 ; C07K7/64 ; C12N15/80 ; A61K38/10
摘要：
This invention is intended to identify a gene cluster involved in biosynthesis of a cyclic peptide compound produced by a filamentous fungus of the Curvularia species and to establish a system for synthesizing such cyclic peptide compound. The gene is composed of a first module to a tenth module and encodes a protein having activity of synthesizing a nonribosomal peptide constituting a basic peptide backbone of a cyclic peptide compound produced by a filamentous fungus of the Curvularia species.
公开/授权文献
信息查询
IPC分类:
