- 专利标题： Recombinant adenoviruses carrying transgenes
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申请号： US15991745申请日： 2018-05-29
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公开(公告)号： US11253608B2公开(公告)日： 2022-02-22
- 发明人: Christopher Larson , Bryan Oronsky , Tony R. Reid
- 申请人： EpicentRx, Inc.
- 申请人地址： US CA La Jolla
- 专利权人： EpicentRx, Inc.
- 当前专利权人： EpicentRx, Inc.
- 当前专利权人地址： US CA La Jolla
- 代理机构： Morrison & Foerster LLP
- 主分类号： C12N15/85
- IPC分类号： C12N15/85 ; A61K47/68 ; A61P35/00 ; A61K47/69 ; C12N7/04 ; A61K48/00 ; C12N15/62 ; C12N7/02 ; C12N15/86
摘要：
Disclosed herein are recombinant adenoviruses with one or more nucleotide sequences inserted between two viral transcription units, formulations comprising the recombinant adenoviruses, and methods of treatment using the recombinant adenoviruses. In some embodiments, the one or more nucleotide sequences are inserted in an IX-E2 insertion site and/or an L5-E4 insertion site.
公开/授权文献
- US20180369404A1 RECOMBINANT ADENOVIRUSES CARRYING TRANSGENES 公开/授权日：2018-12-27
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