Invention Grant
- Patent Title: Autosomal-identical pluripotent stem cell populations having non-identical sex chromosomal composition and uses thereof
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Application No.: US16071094Application Date: 2017-01-31
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Publication No.: US11261433B2Publication Date: 2022-03-01
- Inventor: Ithai Waldhorn , Benjamin Eithan Reubinoff
- Applicant: Hadasit Medical Research Services and Development Ltd.
- Applicant Address: IL Jerusalem
- Assignee: Hadasit Medical Research Services and Development Ltd.
- Current Assignee: Hadasit Medical Research Services and Development Ltd.
- Current Assignee Address: IL Jerusalem
- International Application: PCT/IL2017/050111 WO 20170131
- International Announcement: WO2017/130205 WO 20170803
- Main IPC: C12N5/074
- IPC: C12N5/074 ; C12Q1/02
Abstract:
An article of manufacture is disclosed which comprises at least two populations of autosomal-identical induced pluripotent stem cells (iPSCs), wherein the complement of sex chromosomes of the first population of the at least two populations is non-identical to the complement of sex chromosomes of the second population of the at least two populations. Uses thereof and methods of generating same are also disclosed.
Public/Granted literature
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