Invention Grant
- Patent Title: Thermostable polymerase inhibitor compositions and methods
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Application No.: US16305858Application Date: 2017-06-06
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Publication No.: US11299739B2Publication Date: 2022-04-12
- Inventor: Sergey G. Lokhov , Alexander A. Gall , Vera Baraznenok , Ekaterina V. Viazovkina , Irina Shishkina , David H. Persing
- Applicant: Cepheid
- Applicant Address: US CA Sunnyvale
- Assignee: Cepheid
- Current Assignee: Cepheid
- Current Assignee Address: US CA Sunnyvale
- Agency: Weaver Austin Villeneuve & Sampson LLP
- Agent Emily M. Haliday
- International Application: PCT/US2017/036225 WO 20170606
- International Announcement: WO2017/214202 WO 20171214
- Main IPC: C12Q1/6853
- IPC: C12Q1/6853 ; C12Q1/686 ; C12N15/115
Abstract:
The present disclosure relates to aptamers for temperature-dependent reversible inhibition of thermostable polymerase activity in order to improve sensitivity and specificity of various reactions and assays involving hot start polynucleotide synthesis. Methods for use of the aptamers and related compositions and kits are also provided.
Public/Granted literature
- US20190316132A1 THERMOSTABLE POLYMERASE INHIBITOR COMPOSITIONS AND METHODS Public/Granted day:2019-10-17
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