- 专利标题: Small molecule stimulators of steroid receptor coactivator proteins and their use in the treatment of cancer
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申请号: US15540386申请日: 2015-12-29
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公开(公告)号: US11312676B2公开(公告)日: 2022-04-26
- 发明人: David Michael Lonard , Lei Wang , Bert W. O'Malley , Jianming Xu , Yongcheng Song , Xiaonan Li , Timothy Gerald Palzkill
- 申请人: BAYLOR COLLEGE OF MEDICINE
- 申请人地址: US TX Houston
- 专利权人: BAYLOR COLLEGE OF MEDICINE
- 当前专利权人: BAYLOR COLLEGE OF MEDICINE
- 当前专利权人地址: US TX Houston
- 代理机构: Kilpatrick Townsend & Stockton LLP
- 国际申请: PCT/US2015/067770 WO 20151229
- 国际公布: WO2016/109470 WO 20160707
- 主分类号: C07C49/753
- IPC分类号: C07C49/753 ; A61K31/444 ; A61K31/45 ; A61K31/4402 ; A61K31/351 ; A61K31/4433 ; A61K31/122 ; A61K31/4545 ; C07D401/06 ; C07D309/38 ; C07D405/06 ; C07D213/68 ; C07D405/12 ; A61P35/00 ; C07C49/697 ; C07D211/86 ; C07D213/50 ; C07D309/32 ; C07D401/14 ; C07D405/14
摘要:
Small molecule stimulators of steroid receptor coactivator (SRC) family proteins are provided, as well as methods for their use in treating or preventing cancer. Also provided are methods for stimulating SRC family proteins in a cell.