公开(公告)号：US20180265444A1

公开(公告)日：2018-09-20

申请号：US15540386

申请日：2015-12-29

Applicant: BAYLOR COLLEGE OF MEDICINE

Inventor： David Michael Lonard ,  Lei Wang ,  Bert W. O'Malley ,  Jianming Xu ,  Yongcheng Song ,  Xiaonan Li ,  Timothy Gerald Palzkill

IPC: C07C49/753 ,  A61P35/00 ,  C07C49/697 ,  C07D213/50 ,  C07D309/32 ,  C07D405/14 ,  C07D211/86 ,  C07D401/14

CPC classification number: C07C49/753 ,  A61K31/122 ,  A61K31/351 ,  A61K31/4402 ,  A61K31/4433 ,  A61K31/444 ,  A61K31/45 ,  A61K31/4545 ,  A61P35/00 ,  C07C49/697 ,  C07C2601/14 ,  C07D211/86 ,  C07D213/50 ,  C07D213/68 ,  C07D309/32 ,  C07D309/38 ,  C07D401/06 ,  C07D401/14 ,  C07D405/06 ,  C07D405/12 ,  C07D405/14

Abstract: Small molecule stimulators of steroid receptor coactivator (SRC) family proteins are provided, as well as methods for their use in treating or preventing cancer. Also provided are methods for stimulating SRC family proteins in a cell.

公开(公告)号：US11312676B2

公开(公告)日：2022-04-26

申请号：US15540386

申请日：2015-12-29

Applicant: BAYLOR COLLEGE OF MEDICINE

Inventor： David Michael Lonard ,  Lei Wang ,  Bert W. O'Malley ,  Jianming Xu ,  Yongcheng Song ,  Xiaonan Li ,  Timothy Gerald Palzkill

IPC: C07C49/753 ,  A61K31/444 ,  A61K31/45 ,  A61K31/4402 ,  A61K31/351 ,  A61K31/4433 ,  A61K31/122 ,  A61K31/4545 ,  C07D401/06 ,  C07D309/38 ,  C07D405/06 ,  C07D213/68 ,  C07D405/12 ,  A61P35/00 ,  C07C49/697 ,  C07D211/86 ,  C07D213/50 ,  C07D309/32 ,  C07D401/14 ,  C07D405/14

Abstract: Small molecule stimulators of steroid receptor coactivator (SRC) family proteins are provided, as well as methods for their use in treating or preventing cancer. Also provided are methods for stimulating SRC family proteins in a cell.