• Patent Title: Process for the preparation of cis-alpha,beta substituted cyclopentanones
  • Application No.: US17273357
    Application Date: 2019-12-16
  • Publication No.: US11339113B2
    Publication Date: 2022-05-24
  • Inventor: Denis JacobyLucia Bonomo
  • Applicant: FIRMENICH SA
  • Applicant Address: CH Satigny
  • Assignee: FIRMENICH SA
  • Current Assignee: FIRMENICH SA
  • Current Assignee Address: CH Satigny
  • Agency: Armstrong Teasdale LLP
  • Priority: EP18214113 20181219
  • International Application: PCT/EP2019/085416 WO 20191216
  • International Announcement: WO2020/127094 WO 20200625
  • Main IPC: C07C67/327
  • IPC: C07C67/327 C07C69/716
Process for the preparation of cis-alpha,beta substituted cyclopentanones
Abstract:
Described herein is a process for the preparation of a mixture of compounds of formula having a weight ratio of the cis-diastereomers to trans-diastereoisomers higher than 1:1, where R1 represents a C1-8 alkyl group, a C2-8 alkenyl group or a C2-8 alkynyl group, each optionally substituted with one or two of a C1-4 alkyl alkoxy ether group and/or a C1-4 alkyl carboxylester group and R2 represents a C1-6 alkyl, a C2-6 alkenyl or a C2-6 alkynyl group, each optionally substituted with a C1-4 alkyl alkoxy ether group, a carboxylic acid group or a C1-4 alkyl carboxylester group and compounds suitable in the process.
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