An aerogel structure body includes a composite layer containing fibrous materials and aerogel, the aerogel being held between the fibrous materials, and an aerogel layer having a first surface on at least one surface of the composite layer and formed of the aerogel, in which the aerogel layer having a second surface opposite to the first surface, the second surface including a projection portion projecting from the second surface, and a density of the aerogel in the projection portion is 0.1% to 3.0% higher than a density of the aerogel in the aerogel layer (flat portion) other than the projection portion. Therefore, the aerogel structure body that is excellent in dimensional stability and heat insulating properties and that can be manufactured with high productivity and a method of manufacturing the same are provided.