A durable, hydrophobic and anti-scratching nano-coating for coating on a glass substrate or surface having a water contact angle of about 90° or more, a reduced coefficient of friction by 50% or more, and a reduced surface roughness compared to those of the glass substrate or surface without the nano-coating is provided, which includes a layer of fluorinated silica derived from sol-gel hydrolysis between one or more tetraalkoxysilanes having at least three alkoxy groups and one or more polyfluorinated silanes having at least a trialkoxysilane and from 15 to 17 fluorine atoms in the presence of a catalyst to a reaction mixture of the sol-gel hydrolysis between the one or more tetraalkoxysilanes and the one or more polyfluorinated silanes, and a solvent. A related method of fabricating the nano-coating via atomization of acid-containing or alkali-containing solution and sol-gel precursor solution onto the glass surface is also provided.