An example of a system for monitoring and treating a medical condition of a patient may include signal inputs to receive patient condition signals indicative of a state of inflammatory bowel disease (IBD), a signal processing circuit configured to process the patient condition signals and generate patient condition parameters indicative of the state of IBD using the processed patient condition signals, and a medical condition analyzer configured to analyze the patient condition parameters and determine the medical condition including the state of IBD using an outcome of the analysis. The patient condition parameters may include one or more physiological marker parameters each representative of a physiological marker of IBD and one or more quality of life parameters each being measure of quality of life of the patient.