Invention Grant
- Patent Title: TRPA1 activity inhibitor
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Application No.: US16495663Application Date: 2018-03-13
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Publication No.: US11464720B2Publication Date: 2022-10-11
- Inventor: Masayuki Takaishi , Fumitaka Fujita , Hironori Shimizu , Shu Sakuyama , Kenya Ishida , Kenji Maruyama
- Applicant: MANDOM CORPORATION , TAKASAGO INTERNATIONAL CORPORATION
- Applicant Address: JP Osaka; JP Tokyo
- Assignee: MANDOM CORPORATION,TAKASAGO INTERNATIONAL CORPORATION
- Current Assignee: MANDOM CORPORATION,TAKASAGO INTERNATIONAL CORPORATION
- Current Assignee Address: JP Osaka; JP Tokyo
- Agency: WHDA, LLP
- Priority: JPJP2017-068027 20170330
- International Application: PCT/JP2018/009696 WO 20180313
- International Announcement: WO2018/180460 WO 20181004
- Main IPC: A61K8/34
- IPC: A61K8/34 ; A61Q5/00 ; A61Q15/00 ; A61Q19/00 ; C07G99/00
Abstract:
This TRPA1 activity inhibitor contains a compound represented by formula (I) wherein R1, R2, R3 and R4 each independently represent a hydrogen atom or a methyl group, and R5, R6, R7 and R8 each independently represent a hydrogen atom, a methyl group or —O—R9—OH (in the formula, R9 represents an alkylene group optionally having a substituent group), provided that at least one group of R5, R6, R7 and R8 is —O—R9—OH.
Public/Granted literature
- US20200022889A1 TRPA1 ACTIVITY INHIBITOR Public/Granted day:2020-01-23
Information query
