- 专利标题: 6-membered aza-heterocyclic containing delta-opioid receptor modulating compounds, methods of using and making the same
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申请号: US16286700申请日: 2019-02-27
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公开(公告)号: US11465980B2公开(公告)日: 2022-10-11
- 发明人: Aimee Crombie Speerschneider , Dennis Shinji Yamashita , Philip Michael Pitis , Michael John Hawkins , Guodong Liu , Tamara Ann Miskowski Daubert , Catherine C. K. Yuan , Robert Borbo Kargbo , Robert Jason Herr , Donna Romero , Gregory J. Pacofsky
- 申请人: Trevena, Inc.
- 申请人地址: US PA Chesterbrook
- 专利权人: Trevena, Inc.
- 当前专利权人: Trevena, Inc.
- 当前专利权人地址: US PA Chesterbrook
- 代理机构: Troutman Pepper Hamilton Sanders LLP
- 主分类号: C07D401/12
- IPC分类号: C07D401/12 ; A61K31/445 ; C07D403/12 ; C07D401/14 ; C07D405/14 ; C07D241/04 ; C07D451/02 ; C07D211/22
摘要:
The present embodiments are directed, in part, to compounds, or pharmaceutically acceptable salts thereof, or pharmaceutical compositions thereof for modulating the activity of delta opioid receptor, biased and/or unbiased, and/or methods for treating pain, migraines, headaches, depression, Parkinsons Disease, anxiety, and/or overactive bladder, and other disorders and conditions described herein or any combination thereof.
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