A method for preparing all-solid-state photonic crystal fiber preform by extrusion by aligning the center of the first jacking end of the first jacking rod with the center of the core outlet mold. The adverse effect on this part of extruded core glass by oxygen or other impurities in air during the extrusion out of the core outlets can be avoided. The defects on the core glass surface and the cladding glass surface can be effectively removed, and the purity and quality of the core component in the obtained fiber preform can be improved.