Invention Grant
- Patent Title: Benzamide or benzamine compounds useful as anticancer agents for the treatment of human cancers
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Application No.: US16139865Application Date: 2018-09-24
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Publication No.: US11548894B2Publication Date: 2023-01-10
- Inventor: Jef DeBrabander , Luis Parada
- Applicant: The Board of Regents of the University of Texas System
- Applicant Address: US TX Austin
- Assignee: The Board of Regents of the University of Texas System
- Current Assignee: The Board of Regents of the University of Texas System
- Current Assignee Address: US TX Austin
- Agency: Parker Highlander PLLC
- Main IPC: C07D487/04
- IPC: C07D487/04 ; C07C205/58 ; C07D207/09 ; C07D209/48 ; C07D211/14 ; C07D213/16 ; C07D213/70 ; C07C205/61 ; C07C235/50 ; C07C255/57 ; C07C271/20 ; C07C323/22 ; C07D401/12 ; C07D307/14 ; C07D295/13 ; C07C323/62
Abstract:
The described invention provides small molecule anti-cancer compounds for treating tumors that respond to cholesterol biosynthesis inhibition. The compounds selectively inhibit the cholesterol biosynthetic pathway in tumor-derived cancer cells, but do not affect normally dividing cells.
Public/Granted literature
- US20190263820A1 BENZAMIDE OR BENZAMINE COMPOUNDS USEFUL AS ANTICANCER AGENTS FOR THE TREATMENT OF HUMAN CANCERS Public/Granted day:2019-08-29
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