公开(公告)号：US20240276871A1

公开(公告)日：2024-08-15

申请号：US18604113

申请日：2024-03-13

申请人： DONGJIN SEMICHEM CO., LTD. ,  SAMSUNG DISPLAY CO., LTD.

发明人： Ho Wan HAM ,  Hyun Cheol AN ,  Byung Cheol MIN ,  Dong Jun KIM ,  Jeong Woo HAN ,  Hyung Jin LEE ,  Ja Eun ANN ,  Dong Yuel KWON ,  Dae Woong LEE ,  Hyeon Jeong IM ,  Yeong Rong PARK ,  Il Soo OH ,  Bo Ra LEE ,  Ill Hun CHO

IPC分类号： H10K85/60 ,  C07C233/58 ,  C07C255/46 ,  C07C323/22 ,  C07D295/215 ,  C07F7/08 ,  C09K11/06 ,  H10K50/858 ,  H10K85/40

CPC分类号： H10K85/615 ,  C07C233/58 ,  C07C255/46 ,  C07C323/22 ,  C07D295/215 ,  C07F7/081 ,  C09K11/06 ,  H10K50/858 ,  H10K85/40 ,  H10K85/626 ,  H10K85/656 ,  C07C2601/14 ,  C07C2601/16 ,  C07C2601/18 ,  C07C2602/42 ,  C07C2602/44 ,  C07C2603/74 ,  C09K2211/1011

摘要： A novel compound for a light emitting device, and an organic light emitting device containing the same are disclosed. The compound for a light emitting device is represented by Formula 1 below:

公开(公告)号：US20230212103A1

公开(公告)日：2023-07-06

申请号：US18085341

申请日：2022-12-20

申请人： HANMI PHARM. CO., LTD.

发明人： Dae Jin KIM ,  Jong Soo LEE ,  SungMin BAE ,  Se Chang KWON

IPC分类号： C07C47/198 ,  A61K39/395 ,  C07C323/22 ,  C07C323/39 ,  C07C233/05 ,  A61K47/50 ,  C07C237/04 ,  A61K38/18 ,  A61K47/60 ,  C07C233/18 ,  C07C323/12 ,  C07D213/71

CPC分类号： C07C47/198 ,  A61K39/395 ,  C07C323/22 ,  C07C323/39 ,  C07C233/05 ,  A61K47/50 ,  C07C237/04 ,  A61K38/18 ,  A61K47/60 ,  C07C233/18 ,  C07C323/12 ,  C07D213/71

摘要： Polyethylene glycol derivatives of the following formula I and uses thereof are disclosed. A method for manufacturing the polyethylene glycol derivatives is also disclosed.

公开(公告)号：US20230183167A1

公开(公告)日：2023-06-15

申请号：US17926216

申请日：2021-05-18

申请人： Bowling Green State University

发明人： Jayaraman Sivaguru ,  Ravichandranath Singathi ,  Sruthy Baburaj

IPC分类号： C07C217/20 ,  C07C255/56 ,  C07C323/22 ,  C08F20/14 ,  C07D303/23 ,  C07F7/08 ,  C08F2/50

CPC分类号： C07C217/20 ,  C07C255/56 ,  C07C323/22 ,  C08F20/14 ,  C07D303/23 ,  C07F7/081 ,  C08F2/50

摘要： Biomass derived benzoin derivatives, and methods of making and using the same, are described. Benzoin derivatives may be used as visible light photoinitiators.

公开(公告)号：US11603346B2

公开(公告)日：2023-03-14

申请号：US16082737

申请日：2017-03-07

申请人： HANMI PHARM. CO., LTD.

发明人： Dae Jin Kim ,  Jong Soo Lee ,  Sung Min Bae ,  Se Chang Kwon

IPC分类号： C07C47/198 ,  A61K39/395 ,  C07C323/22 ,  C07C323/39 ,  C07C233/05 ,  A61K47/50 ,  C07C237/04 ,  A61K38/18 ,  A61K47/60 ,  C07C233/18 ,  C07C323/12 ,  C07D213/71

摘要： The present invention relates to polyethylene glycol derivatives and use thereof.

公开(公告)号：US11413255B2

公开(公告)日：2022-08-16

申请号：US15735214

申请日：2016-06-27

申请人： Montefiore Medical Center

发明人： Richard M. LoPachin ,  Terrence Gavin ,  Brian Geohagen

IPC分类号： A61K31/167 ,  A61K31/191 ,  A61K31/122 ,  A61K31/12 ,  C07C49/825 ,  C07C49/82 ,  C07C49/835 ,  C07C49/78 ,  C07C233/33 ,  C07C323/22 ,  A61K31/495 ,  A61K31/05 ,  A61K31/095 ,  A61K31/36 ,  A61P39/06 ,  A01N1/02 ,  A61K31/381 ,  A61K31/402 ,  A61K31/5375 ,  C07C49/80 ,  C07C49/807 ,  C07C49/84 ,  C07D207/04 ,  C07D207/325 ,  C07D295/112 ,  C07D333/22

摘要： Methods, filters and compositions are disclosed for treating toxicity due to oxidative stress and toxic electrophiles.

公开(公告)号：US20210040052A1

公开(公告)日：2021-02-11

申请号：US16965720

申请日：2019-01-18

申请人： DEMOTECH.INC.

发明人： Song LU ,  Wenwei XIE ,  Shuangjiang HE

IPC分类号： C07D265/30 ,  C07C323/22 ,  C07D311/58 ,  C07D339/04 ,  C07D495/04 ,  C07D249/08

摘要： The present invention relates to the field of compounds, and in particular to a probucol derivative, a preparation method therefor and use thereof, the probucol derivative having a structure represented by general formula I. The probucol derivative provided in the present invention can be used for the prevention and treatment of vascular diseases including diabetes, cardio-cerebrovascular diseases or complications thereof, and can be effectively used for reducing blood glucose, reducing blood lipid, reducing cholesterol, reducing body weight, reducing triglyceride, anti-inflammatory, and anti-oxidation, etc., having broad prospective applications.

公开(公告)号：US10172866B2

公开(公告)日：2019-01-08

申请号：US15087811

申请日：2016-03-31

申请人： Arrien Pharmaceuticals LLC

发明人： Hariprasad Vankayalapati ,  Venkatakrishnareddy Yerramreddy

IPC分类号： C07D295/116 ,  C07D401/10 ,  C07D295/135 ,  C07D213/50 ,  C07D211/14 ,  C07D231/12 ,  C07D277/42 ,  C07D211/38 ,  C07D211/58 ,  A61K31/5375 ,  C07C323/22 ,  A61K31/451 ,  A61K31/4545 ,  A61K31/495 ,  A61K31/496 ,  A61K31/5377 ,  A61K31/122 ,  A61K31/255 ,  A61K31/44 ,  A61K31/445

摘要： The present invention is directed to compounds, their synthesis, and their use as antagonists, inverse agonists, modulators and or inhibitors of the Retinoic acid-related orphan nuclear receptor γt (RORγt)/RORγ. The compounds of the present invention are useful for modulating RORγt)/RORγ activity and for treating diseases or conditions mediated by RORγt)/RORγ such as for example, disease states associated with immunopathology of human autoimmune diseases such as Multiple Sclerosis (MS), Rheumatoid Arthritis (RA), Inflammatory Colitis, Psoriasis, COPD, Pain, Obesity, Diabetes, Dyslipidemia, Osteoporosis, Asthma, Neurodegenerative diseases and Cancer.

公开(公告)号：US09956448B2

公开(公告)日：2018-05-01

申请号：US14776057

申请日：2014-03-14

申请人： Tyco Fire Products LP

发明人： Thomas Joseph Martin

IPC分类号： A62D1/02 ,  A62D1/00 ,  C07C323/22 ,  C08G75/02

CPC分类号： A62D1/0085 ,  A62D1/0042 ,  C07C323/22 ,  C08G75/02

摘要： Novel fluorosurfactants are provided that contain perfluoroalkyl groups no longer than perfluorohexyl (C6). The surfactants are useful in the preparation of aqueous film forming foams (AFFF) and alcohol-resistant film-forming foams (AR-AFFF) for firefighting. Unexpectedly, these compounds have activity in AFFF and AR-AFFF applications that is comparable and even superior to conventional surfactants that contain perfluoroalkyl groups that are perfluorooctyl (C8) and longer. Also provided are methods of making the novel surfactants, as well as foam concentrates, methods of making foam and methods of fighting fires using foam containing the novel surfactants.

公开(公告)号：US09908845B2

公开(公告)日：2018-03-06

申请号：US14905776

申请日：2014-09-05

申请人： Peloton Therapeutics, Inc.

发明人： Darryl David Dixon ,  Jonas Grina ,  John A. Josey ,  James P. Rizzi ,  Stephen T. Schlachter ,  Eli M. Wallace ,  Bin Wang ,  Paul Wehn ,  Rui Xu ,  Hanbiao Yang

IPC分类号： C07C317/22 ,  C07C43/225 ,  C07C43/23 ,  A61K31/09 ,  A61K31/10 ,  C07C311/29 ,  C07C43/285 ,  C07C43/205 ,  C07C43/263 ,  C07C255/54 ,  C07C255/56 ,  C07C205/22 ,  C07C313/06 ,  C07C317/24 ,  C07C317/32 ,  C07C317/34 ,  C07C317/36 ,  C07C317/40 ,  C07C317/42 ,  C07C317/44 ,  C07C317/46 ,  C07C317/48 ,  C07C323/22 ,  C07C381/10 ,  C07D213/89 ,  C07D231/56 ,  C07D213/65 ,  C07D213/85

CPC分类号： C07D213/85 ,  A61K31/09 ,  A61K31/10 ,  A61K41/0038 ,  A61P35/00 ,  C07C43/205 ,  C07C43/225 ,  C07C43/23 ,  C07C43/263 ,  C07C43/275 ,  C07C43/285 ,  C07C43/29 ,  C07C205/22 ,  C07C255/54 ,  C07C255/56 ,  C07C311/29 ,  C07C313/06 ,  C07C317/22 ,  C07C317/24 ,  C07C317/32 ,  C07C317/34 ,  C07C317/36 ,  C07C317/40 ,  C07C317/42 ,  C07C317/44 ,  C07C317/46 ,  C07C317/48 ,  C07C323/22 ,  C07C381/10 ,  C07C2602/04 ,  C07C2602/08 ,  C07C2602/10 ,  C07C2603/94 ,  C07D213/65 ,  C07D213/89 ,  C07D231/56

摘要： The present disclosure relates to HIF-2α inhibitors and methods of making and using them for treating cancer. Certain compounds were potent in HIF-2α scintillation proximity assay, luciferase assay, and VEGF ELISA assay, and led to tumor size reduction and regression in 786-O xenograft bearing mice in vivo.

公开(公告)号：US09346749B2

公开(公告)日：2016-05-24

申请号：US14126479

申请日：2012-06-18

申请人： Young Sik Jung ,  Chong Kgo Lee ,  Ihl Young Choi ,  Hae Soo Kim ,  Pil Ho Kim ,  Soo Bong Han ,  Johan Neyts ,  Hendrik Jan Thibaut

发明人： Young Sik Jung ,  Chong Kgo Lee ,  Ihl Young Choi ,  Hae Soo Kim ,  Pil Ho Kim ,  Soo Bong Han ,  Johan Neyts ,  Hendrik Jan Thibaut

IPC分类号： A61K31/122 ,  A61K31/435 ,  C07D221/04 ,  C07C49/747 ,  C07C269/00 ,  C07C271/24 ,  C07C271/44 ,  C07C271/64 ,  C07C275/26 ,  C07C275/64 ,  C07C205/45 ,  C07C323/22 ,  C07C225/20 ,  C07C225/22 ,  C07C233/32 ,  C07C233/33 ,  C07C233/41 ,  C07C233/43 ,  C07C233/61 ,  C07C233/76 ,  C07C247/14 ,  C07C69/16 ,  C07C69/18 ,  C07C69/28 ,  C07C69/54 ,  C07C69/618 ,  C07C69/63 ,  C07C69/738 ,  C07C69/78 ,  C07C49/753 ,  C07D215/20 ,  C07D213/65 ,  C07C45/00 ,  C07C67/00 ,  C07C69/12 ,  C07C69/22 ,  C07C69/736

CPC分类号： A61K31/122 ,  A61K31/435 ,  C07C45/00 ,  C07C49/747 ,  C07C49/753 ,  C07C49/755 ,  C07C67/00 ,  C07C67/08 ,  C07C69/12 ,  C07C69/16 ,  C07C69/18 ,  C07C69/22 ,  C07C69/28 ,  C07C69/54 ,  C07C69/618 ,  C07C69/63 ,  C07C69/736 ,  C07C69/738 ,  C07C69/78 ,  C07C205/45 ,  C07C225/20 ,  C07C225/22 ,  C07C231/02 ,  C07C233/32 ,  C07C233/33 ,  C07C233/41 ,  C07C233/43 ,  C07C233/61 ,  C07C233/76 ,  C07C247/14 ,  C07C269/00 ,  C07C271/12 ,  C07C271/24 ,  C07C271/44 ,  C07C271/64 ,  C07C275/26 ,  C07C275/64 ,  C07C323/22 ,  C07C2601/02 ,  C07C2602/08 ,  C07D213/65 ,  C07D215/20 ,  C07D221/04

摘要： Disclosed are 1,3-Dioxoindene derivatives, pharmaceutically acceptable salts thereof or enantiomers, a preparation method thereof, and a pharmaceutical composition for the prevention or treatment of viral diseases, comprising the same as an active ingredient. The 1,3-Dioxoindene derivatives have excellent inhibitory activity against picornaviruses including coxsackie-, entero-, echo-, Polio-, and rhinoviruses, as well as exhibiting low cytotoxicity, so that they can be useful as an active ingredient of a pharmaceutical composition for the prevention or treatment of viral diseases including poliomyelitis, paralysis, acute hemorrhagic conjunctivitis, viral meningitis, hand-foot-and-mouth disease, vesicular disease, hepatitis A, myositis, myocarditis, pancreatitis, diabetes, epidemic myalgia, encephalitis, flu, herpangina, foot-and-mouth disease, asthma, chronic obstructive pulmonary disease, pneumonia, sinusitis or otitis media.

摘要翻译： 公开了1,3-二氧代茚衍生物，其药学上可接受的盐或对映异构体，其制备方法和用于预防或治疗病毒性疾病的药物组合物，其包含其作为活性成分。 1,3-二氧代茚衍生物对包括柯萨奇，肠，回波，脊髓灰质炎和鼻病毒在内的小核糖核酸病毒具有优异的抑制活性，并且具有低的细胞毒性，因此它们可用作药物组合物的活性成分 用于预防或治疗包括脊髓灰质炎，麻痹，急性出血性结膜炎，病毒性脑膜炎，手足口病，囊泡病，甲型肝炎，肌炎，心肌炎，胰腺炎，糖尿病，流行性肌痛，脑炎，流感， 麻疹，口蹄疫，哮喘，慢性阻塞性肺病，肺炎，鼻窦炎或中耳炎。