- 专利标题: Compounds and methods for regulating insulin secretion
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申请号: US16494744申请日: 2018-03-19
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公开(公告)号: US11555031B2公开(公告)日: 2023-01-17
- 发明人: Sean M. Burns , Bridget K. Wagner , Amedeo Vetere
- 申请人: The Broad Institute, Inc. , The General Hospital Corporation , Instituto Carlos Slim de la Salud, A.C.
- 申请人地址: US MA Cambridge; US MA Boston; MX Mexico City
- 专利权人: The Broad Institute, Inc.,The General Hospital Corporation,Instituto Carlos Slim de la Salud, A.C.
- 当前专利权人: The Broad Institute, Inc.,The General Hospital Corporation,Instituto Carlos Slim de la Salud, A.C.
- 当前专利权人地址: US MA Cambridge; US MA Boston; MX Mexico City
- 代理机构: Greenberg Traurig, LLP
- 代理商 Melissa Hunter-Ensor; Scott Goncher
- 国际申请: PCT/US2018/023149 WO 20180319
- 国际公布: WO2018/175324 WO 20180927
- 主分类号: C07D413/12
- IPC分类号: C07D413/12 ; A61P3/08 ; C07C235/84 ; C07D213/30 ; C07D231/12 ; C07D237/08 ; C07D261/08 ; C07D495/04
摘要:
Disclosed herein are methods for inducing insulin secretion in a glucose-dependent manner and compounds for use in these methods. The compounds may have the structure of formula I(a): wherein the substituents are as described in the description; or a pharmaceutically acceptable form thereof.
公开/授权文献
- US20200017485A1 COMPOUNDS AND METHODS FOR REGULATING INSULIN SECRETION 公开/授权日:2020-01-16