- 专利标题: Promoter of Hspa5 gene
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申请号: US16338941申请日: 2017-10-02
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公开(公告)号: US11555204B2公开(公告)日: 2023-01-17
- 发明人: Kenji Masuda , Koichi Nonaka , Hiroki Tanemura
- 申请人: Daiichi Sankyo Company, Limited
- 申请人地址: JP Tokyo
- 专利权人: Daiichi Sankyo Company, Limited
- 当前专利权人: Daiichi Sankyo Company, Limited
- 当前专利权人地址: JP Tokyo
- 代理机构: Christenser O'Connor Johnson Kindness PLLC
- 优先权: JPJP2016-195564 20161003
- 国际申请: PCT/JP2017/035773 WO 20171002
- 国际公布: WO2018/066492 WO 20180412
- 主分类号: C12N15/85
- IPC分类号: C12N15/85 ; C12P21/02 ; C12N15/113 ; C12N15/09 ; C12N5/10
摘要:
The present invention provides an approach to enhancing the production of a foreign protein serving as a protein-based pharmaceutical product in host cells such as cultured cells derived from a mammal. The present invention provides transformed cells having a novel Hspa5 gene promoter, and a method for secreting and producing a foreign protein at high levels using the transformed host cells.
公开/授权文献
- US20190241907A1 Promoter of Hspa5 Gene 公开/授权日:2019-08-08
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