Methods and devices for creating and operating a combined network and computational slice instance (NCSI) in a Multi-access Edge Computing (MEC) scenario. Communication and computational resources may be reserved by a NCSI controller for the NCSI. The communication resources may include network slices and the computational resources may include MEC computational resources of one or more MEC servers. The reserved resources may be selected based on quality of service (QoS) requirements of UEs that will utilize the NCSI. During operation, reserved resources for the NCSI may be dynamically renegotiated based on an aggregate load of the NCSI, the QoS of data traffic, and/or updated QoS requirements of the UEs.