This application relates to computing circuitry (200), in particular for analogue computing circuitry suitable for neuromorphic computing. The circuitry (200) has a plurality of memory cells (201), each memory cell having an input electrode (201) for receiving a cell input signal and an output (203P, 203N) for outputting a cell output signal (IP, IN), with first and second paths connecting the input electrode to the output. The cell output signal thus depends on a differential current between the first and second paths due to the cell input signal. Each memory cell also comprises at least one programmable-resistance memory element (204) in each of the first and second paths and is controllable, by selective programming of the programmable-resistance memory elements, to store a data digit that can take any of at least three different values. The plurality of memory cells are configured into one or more sets (205) of memory cells and a combiner module (206) receives the cell output signals from each of the memory cells in at least one set, and combines the cell output signals with a different scaling factor applied to each of the cell output signals.