Invention Grant
- Patent Title: Composition and method for modulating fibroblast growth factor receptor 3 activation
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Application No.: US16484948Application Date: 2018-02-08
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Publication No.: US11630102B2Publication Date: 2023-04-18
- Inventor: Yuan-Tsong Chen , Yi-Ching Lee , Jer-Yuam Wu , Hsiao-Jung Kao
- Applicant: ACADEMIA SINICA
- Applicant Address: TW Taipei
- Assignee: ACADEMIA SINICA
- Current Assignee: ACADEMIA SINICA
- Current Assignee Address: TW Taipei
- Agency: Birch, Stewart, Kolasch & Birch, LLP
- International Application: PCT/US2018/017376 WO 20180208
- International Announcement: WO2018/148376 WO 20180816
- Main IPC: A01K67/027
- IPC: A01K67/027 ; G01N33/50 ; A61P19/00 ; A61P35/00 ; A61K31/409 ; A61K36/21
Abstract:
A method of inhibiting an overactive fibroblast growth factor receptor 3 (FGFR3) in a cell by contacting the cell with a composition that contains an effective amount of Pheophorbide a, Pyropheophorbide a, or an active derivative thereof. Also disclosed is a method for treating a disorder associated with an overactive FGFR3 with a composition containing an effective amount of Pheophorbide a, Pyropheophorbide a, or an active derivative thereof. Further, a composition for treating a disorder associated with an overactive FGFR3 is described. The composition contains an ethanol extract of Amaranthus viridis.
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