Invention Grant
- Patent Title: Bicyclic compounds for use as RIP1 kinase inhibitors
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Application No.: US16844952Application Date: 2020-04-09
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Publication No.: US11673892B2Publication Date: 2023-06-13
- Inventor: Huifen Chen , Gregory Hamilton , Snahel Patel , Guiling Zhao , Blake Daniels , Craig Stivala
- Applicant: Genentech, Inc.
- Applicant Address: US CA South San Francisco
- Assignee: Genentech, Inc.
- Current Assignee: Genentech, Inc.
- Current Assignee Address: US CA South San Francisco
- Agent Jelena Libby
- Main IPC: C07D487/04
- IPC: C07D487/04 ; C07D519/00 ; A61P25/28 ; A61K31/4196 ; A61P25/16
Abstract:
The invention provides novel compounds having the general formula I:
or pharmaceutically acceptable salts thereof, wherein
RA, RB1, RB2, the A ring and the B ring are as described herein, pharmaceutical compositions including the compounds, and methods of using the compounds.
or pharmaceutically acceptable salts thereof, wherein
RA, RB1, RB2, the A ring and the B ring are as described herein, pharmaceutical compositions including the compounds, and methods of using the compounds.
Public/Granted literature
- US20200283446A1 BICYCLIC COMPOUNDS FOR USE AS RIP1 KINASE INHIBITORS Public/Granted day:2020-09-10
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